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Safe, Comprehensive Coverage

Veterinarians choose Vira Shield^® for convenient, one-bottle vaccination against reproductive and respiratory viruses for many reasons:

• 12-month duration of immunity (DOI) label claim for Lepto hardjo-bovis (LHB), the most common cause of leptospirosis in the U.S.¹
• Up to 13 disease-fighting antigens in one ready-to-use bottle
• Safe for use on all cattle, even pregnant cows and heifers
• The only vaccine to feature 3-way BVD coverage including cytopathic (CP) Type 1, noncytopathic (NCP) Type 1 and Type 2
• Demonstrated to deliver enhanced IBR fetal protection eight months postvaccination²
• Provides both humoral and cell-mediated immunity
• Powerful, long-lasting control with state-of-the-art adjuvant, Xtend^® SP

For more detailed information about Vira Shield, visit our literature library.

1. Data on file at Novartis Animal Health US, Inc. 2011
2. Zimmerman A., et al. Efficacy of bovine herpesviurs-1 inactivated vaccine against abortion and stillbirth in pregnant heifers. JAVMA. 2007; 231:1386-1389.

 

 

Protect Against the Most Threatening Diseases

Vira Shield offers proven protection against common diseases that can threaten your herd and your profitability.

BVD Protection Unlike Any Other

As the only vaccine to feature three-way BVD coverage, Vira Shield HB eliminates the hassle of using multiple products for complete respiratory and reproductive control. Research shows that 98 to 99 percent of field samples diagnosed are NCP BVD¹

 

 

 

Protect Against IBR Abortion

Veterinary diagnostic labs are reporting a significant increase in the number of IBR abortions in pregnant heifers and cows. In a fetal protection study, animals vaccinated with Vira Shield 6 and nonvaccinated animals in the control group were challenged with virulent IBR at approximately six months of gestation and almost eight months postvaccination².

 

If you want to learn more about IBR, select one of the following:
Prevention & Progress on IBR and Safety
Talking IBR Advertorial

 

 

 

Providing a Cell-Mediated Immune (CMI) Response

To deliver the most effective immune response against viral diseases like BVD, IBR and BRSV a vaccine needs to produce two distinct types of immunity—humoral and cell-mediated.

• Research shows Vira Shield stimulates a highly effective CMI response to BVD through the production of antigen-specific interferon gamma³.
• Additional research found that an adjuvanted, inactivated vaccine provided a much stronger CMI response to BRSV than MLVs⁴.

For more information on CMI, select one of the following:
CMI Technical Update
Prevention & Progress on CMI

 

1. Brock, K. Department of Pathobiology, Auburn University College of Veterinary Medicine, Auburn, AL.
2. IBR Abortions on the Increase. Colorado State University Veterinary Diagnostic Lab. Lablines Spring/Summer 2009. Volume 14, Number 1.
3. Stevens E.T., et al. The induction of a cell-mediated immune response to bovine viral diarrhea virus with an adjuvanted inactivated vaccine. MediMedia Animal Health. 2009; E1 – E8.
4. Sandbulte MR, Roth JA. Priming of multiple T-cell subsets by modified-live and inactivated bovine respiratory syncytial virus vaccines. Veterinary Immunology and Immunopathology 2003; 95:123-133.